Epigenetics-based cervical cancer diagnostics. The GynTect® test detects aberrant DNA methylation patterns to identify cervical cancer and high-grade precancerous lesions with high specificity — enabling targeted treatment decisions for HPV-positive patients.
Cervical cancer is the fourth most common cancer in women worldwide. While HPV testing has dramatically improved early detection, HPV-positive results require further differentiation: not every HPV infection leads to cancer. oncgnostics' GynTect® test fills this gap.
GynTect® detects aberrant methylation of six epigenetic markers in cervical cells — patterns that are specifically associated with the development of cervical cancer. The test provides high specificity to identify which HPV-positive patients have cancer or high-grade precancerous lesions requiring immediate treatment.
Founded in Jena in 2012 from research at the Leibniz Institute on Aging (Fritz Lipmann Institute), oncgnostics has validated GynTect® in clinical studies across Europe and licensed the technology to partners in China and other markets. Dr. Peter Haug co-founded the company and led Business Development, contributing to Series A fundraising, crowdfunding campaigns and the China licensing deal.
Major milestones in oncgnostics' development — from Series A through crowdfunding success and the landmark China licensing agreement.
Seegene Germany GmbH announced on 2 December 2025 the continuation of its strategic cooperation with Epitype GmbH — the successor company to oncgnostics, now part of the MDG Molecular Diagnostics Group. Epitype retained oncgnostics' patents, production site in Jena and core team. The partnership focuses on jointly marketing epigenetic cervical cancer tests in Europe, integrating Epitype's ScreenYu Gyn® diagnostic solution into Seegene's European multiplex PCR portfolio. Dr. Lothar Kruska, Managing Director of Seegene Germany: "Gemeinsam schaffen wir Lösungen, die die Krebsfrüherkennung auf ein neues Niveau heben."
Seegene Germany press release, December 2025oncgnostics GmbH was acquired by the Molecular Diagnostics Group (MDG / Molecular Biotech AG) and rebranded as Epitype GmbH. The acquisition secured the continuation of oncgnostics' epigenetic cervical cancer diagnostics technology, with the company retaining its production site in Jena and its core research and development team. The new name, Epitype, reflects the company's focus on epigenetic typing of cancer precursors. For the latest information, visit molecular-diagnostics-group.com.
MDG Molecular Diagnostics Group / Epitype GmbHoncgnostics GmbH signed a licensing agreement with a Chinese diagnostics company for the GynTect® cervical cancer test, opening access to one of the world's largest markets. The Chinese partner received rights to commercialize GynTect®-based testing in China, where cervical cancer remains a major public health challenge.
oncgnostics / 360Dx / GenomeWeb, August 2022oncgnostics GmbH successfully closed a €1 million Series A round to support clinical trials of its epigenetic cervical cancer test GynTect®. The financing enables a pivotal clinical validation study across multiple European sites, a key milestone on the path to CE certification and commercialization.
GenomeWeb / oncgnostics press release, January 2015Building on a successful first crowdfunding campaign, oncgnostics launched and completed a second round of equity crowdfunding, demonstrating continued retail investor confidence in the GynTect® platform and its commercial potential in the growing market for HPV triage testing.
Transkript / oncgnostics, 2018oncgnostics GmbH was recognised as one of the Top 50 Start-ups in Germany, acknowledging the innovative potential of the epigenetic approach to cervical cancer diagnostics and the company's progress toward clinical validation and market entry.
Top 50 Start-up Germany, 2017For the latest information about GynTect® and oncgnostics, please visit the company website directly.
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